LMNA-PTN Fusion FISH Probe
The LMNA-PTN Fusion FISH Probe is used to confirm a fusion of the LMNA and PTN genes. The fusion of the LMNA and PTN genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LMNA-PTN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-RERE | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-REOR | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-REGO | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-REGR | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-OROR | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-GORE | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-GROR | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| LMNA-PTN-20-AQAQ | 20 (40 μL) | 200 μL |
|
LMNA Gene Summary
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
Gene Name: Lamin A/C
Chromosome: CHR1: 156084460 -156109878
Locus: 1q22
PTN Gene Summary
The protein encoded by this gene is a secreted heparin-binding growth factor. The protein has significant roles in cell growth and survival, cell migration, angiogenesis and tumorigenesis. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Gene Name: Pleiotrophin
Chromosome: CHR7: 136912091 -137028546
Locus: 7q33
Gene Diseases
The LMNA PTN Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|