LNPEP-PPIP5K2 Fusion FISH Probe
The LNPEP-PPIP5K2 Fusion FISH Probe is used to confirm a fusion of the LNPEP and PPIP5K2 genes. The fusion of the LNPEP and PPIP5K2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LNPEP-PPIP5K2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-RERE | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-REOR | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-REGO | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-REGR | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-REAQ | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-ORRE | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-OROR | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-ORGO | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-ORAQ | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-GORE | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-GOOR | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-GOGO | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-GOGR | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-GOAQ | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-GRRE | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-GROR | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-GRGO | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-GRGR | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-GRAQ | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-AQRE | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-AQOR | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-AQGO | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-AQGR | 20 (40 μL) | 200 μL |
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| LNPEP-PPIP5K2-20-AQAQ | 20 (40 μL) | 200 μL |
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LNPEP Gene Summary
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Leucyl And Cystinyl Aminopeptidase
Chromosome: CHR5: 96271345 -96365115
Locus: 5q15
PPIP5K2 Gene Summary
This gene encodes a member of the histidine acid phosphatase family of proteins. Despite containing a histidine acid phosphatase domain, the encoded protein functions as an inositol pyrophosphate kinase, and is thought to lack phosphatase activity. This kinase activity is the mechanism by which the encoded protein synthesizes high-energy inositol pyrophosphates, which act as signaling molecules that regulate cellular homeostasis and other processes. This gene may be associated with autism spectrum disorder in human patients. [provided by RefSeq, Sep 2016]
Gene Name: Diphosphoinositol Pentakisphosphate Kinase 2
Chromosome: CHR5: 102465256 -102538909
Locus: 5q21.1
Gene Diseases
The LNPEP PPIP5K2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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