LONP1-DUS3L Fusion FISH Probe
The LONP1-DUS3L Fusion FISH Probe is used to confirm a fusion of the LONP1 and DUS3L genes. The fusion of the LONP1 and DUS3L genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LONP1-DUS3L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-RERE | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-REOR | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-REGO | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-REGR | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-REAQ | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-ORRE | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-OROR | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-ORGO | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-ORAQ | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-GORE | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-GOOR | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-GOGO | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-GOGR | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-GOAQ | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-GRRE | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-GROR | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-GRGO | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-GRGR | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-GRAQ | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-AQRE | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-AQOR | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-AQGO | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-AQGR | 20 (40 μL) | 200 μL |
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| LONP1-DUS3L-20-AQAQ | 20 (40 μL) | 200 μL |
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LONP1 Gene Summary
This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]
Gene Name: Lon Peptidase 1, Mitochondrial
Chromosome: CHR19: 5691844 -5720176
Locus: 19p13.3
DUS3L Gene Summary
The Dihydrouridine Synthase 3 Like (DUS3L) gene is located on chr19 :5785152-5791249 at 19p13.3.
Gene Name: Dihydrouridine Synthase 3 Like
Chromosome: CHR19: 5785152 -5791249
Locus: 19p13.3
Gene Diseases
The LONP1 DUS3L Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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