LPCAT1-DAP Fusion FISH Probe
The LPCAT1-DAP Fusion FISH Probe is used to confirm a fusion of the LPCAT1 and DAP genes. The fusion of the LPCAT1 and DAP genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LPCAT1-DAP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-RERE | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-REOR | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-REGO | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-REGR | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-REAQ | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-ORRE | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-OROR | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-ORGO | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-ORAQ | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-GORE | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-GOOR | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-GOGO | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-GOGR | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-GOAQ | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-GRRE | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-GROR | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-GRGO | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-GRGR | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-GRAQ | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-AQRE | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-AQOR | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-AQGO | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-AQGR | 20 (40 μL) | 200 μL |
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| LPCAT1-DAP-20-AQAQ | 20 (40 μL) | 200 μL |
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DAP Gene Summary
This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Gene Name: Death Associated Protein
Chromosome: CHR5: 10679341 -10761387
Locus: 5p15.2
LPCAT1 Gene Summary
This gene encodes a member of the 1-acyl-sn-glycerol-3-phosphate acyltransferase family of proteins. The encoded enzyme plays a role in phospholipid metabolism, specifically in the conversion of lysophosphatidylcholine to phosphatidylcholine in the presence of acyl-CoA. This process is important in the synthesis of lung surfactant and platelet-activating factor (PAF). Elevated expression of this gene may contribute to the progression of oral squamous cell, prostate, breast, and other human cancers. [provided by RefSeq, Sep 2016]
Gene Name: Lysophosphatidylcholine Acyltransferase 1
Chromosome: CHR5: 1461541 -1524076
Locus: 5p15.33
Gene Diseases
The LPCAT1 DAP Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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