SEARCH OUR PRODUCT CATALOG

LRBA-DLG2 Fusion FISH Probe

The LRBA-DLG2 Fusion FISH Probe is used to confirm a fusion of the LRBA and DLG2 genes. The fusion of the LRBA and DLG2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
LRBA-DLG2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
LRBA-DLG2-20-RERE 20 (40 μL) 200 μL
LRBA-DLG2-20-REOR 20 (40 μL) 200 μL
LRBA-DLG2-20-REGO 20 (40 μL) 200 μL
LRBA-DLG2-20-REGR 20 (40 μL) 200 μL
LRBA-DLG2-20-REAQ 20 (40 μL) 200 μL
LRBA-DLG2-20-ORRE 20 (40 μL) 200 μL
LRBA-DLG2-20-OROR 20 (40 μL) 200 μL
LRBA-DLG2-20-ORGO 20 (40 μL) 200 μL
LRBA-DLG2-20-ORAQ 20 (40 μL) 200 μL
LRBA-DLG2-20-GORE 20 (40 μL) 200 μL
LRBA-DLG2-20-GOOR 20 (40 μL) 200 μL
LRBA-DLG2-20-GOGO 20 (40 μL) 200 μL
LRBA-DLG2-20-GOGR 20 (40 μL) 200 μL
LRBA-DLG2-20-GOAQ 20 (40 μL) 200 μL
LRBA-DLG2-20-GRRE 20 (40 μL) 200 μL
LRBA-DLG2-20-GROR 20 (40 μL) 200 μL
LRBA-DLG2-20-GRGO 20 (40 μL) 200 μL
LRBA-DLG2-20-GRGR 20 (40 μL) 200 μL
LRBA-DLG2-20-GRAQ 20 (40 μL) 200 μL
LRBA-DLG2-20-AQRE 20 (40 μL) 200 μL
LRBA-DLG2-20-AQOR 20 (40 μL) 200 μL
LRBA-DLG2-20-AQGO 20 (40 μL) 200 μL
LRBA-DLG2-20-AQGR 20 (40 μL) 200 μL
LRBA-DLG2-20-AQAQ 20 (40 μL) 200 μL

LRBA Gene Summary

The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

Gene Name: LPS Responsive Beige-like Anchor Protein

Chromosome: CHR4: 151185810 -151936649

Locus: 4q31.3

DLG2 Gene Summary

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known. [provided by RefSeq, Dec 2008]

Gene Name: Discs Large MAGUK Scaffold Protein 2

Chromosome: CHR11: 83166055 -85338314

Locus: 11q14.1

Gene Diseases

The LRBA DLG2 Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.