SEARCH OUR PRODUCT CATALOG

LRBA-RXFP1 Fusion FISH Probe

The LRBA-RXFP1 Fusion FISH Probe is used to confirm a fusion of the LRBA and RXFP1 genes. The fusion of the LRBA and RXFP1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
LRBA-RXFP1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
LRBA-RXFP1-20-RERE 20 (40 μL) 200 μL
LRBA-RXFP1-20-REOR 20 (40 μL) 200 μL
LRBA-RXFP1-20-REGO 20 (40 μL) 200 μL
LRBA-RXFP1-20-REGR 20 (40 μL) 200 μL
LRBA-RXFP1-20-REAQ 20 (40 μL) 200 μL
LRBA-RXFP1-20-ORRE 20 (40 μL) 200 μL
LRBA-RXFP1-20-OROR 20 (40 μL) 200 μL
LRBA-RXFP1-20-ORGO 20 (40 μL) 200 μL
LRBA-RXFP1-20-ORAQ 20 (40 μL) 200 μL
LRBA-RXFP1-20-GORE 20 (40 μL) 200 μL
LRBA-RXFP1-20-GOOR 20 (40 μL) 200 μL
LRBA-RXFP1-20-GOGO 20 (40 μL) 200 μL
LRBA-RXFP1-20-GOGR 20 (40 μL) 200 μL
LRBA-RXFP1-20-GOAQ 20 (40 μL) 200 μL
LRBA-RXFP1-20-GRRE 20 (40 μL) 200 μL
LRBA-RXFP1-20-GROR 20 (40 μL) 200 μL
LRBA-RXFP1-20-GRGO 20 (40 μL) 200 μL
LRBA-RXFP1-20-GRGR 20 (40 μL) 200 μL
LRBA-RXFP1-20-GRAQ 20 (40 μL) 200 μL
LRBA-RXFP1-20-AQRE 20 (40 μL) 200 μL
LRBA-RXFP1-20-AQOR 20 (40 μL) 200 μL
LRBA-RXFP1-20-AQGO 20 (40 μL) 200 μL
LRBA-RXFP1-20-AQGR 20 (40 μL) 200 μL
LRBA-RXFP1-20-AQAQ 20 (40 μL) 200 μL

LRBA Gene Summary

The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

Gene Name: LPS Responsive Beige-like Anchor Protein

Chromosome: CHR4: 151185810 -151936649

Locus: 4q31.3

RXFP1 Gene Summary

This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Gene Name: Relaxin/insulin Like Family Peptide Receptor 1

Chromosome: CHR4: 159443046 -159573263

Locus: 4q32.1

Gene Diseases

The LRBA RXFP1 Fusion has been associated with the following diseases:

Disease Name
Bladder Urothelial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.