LRP11-ULBP2 Fusion FISH Probe
The LRP11-ULBP2 Fusion FISH Probe is used to confirm a fusion of the LRP11 and ULBP2 genes. The fusion of the LRP11 and ULBP2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LRP11-ULBP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-RERE | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-REOR | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-REGO | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-REGR | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-REAQ | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-ORRE | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-OROR | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-ORGO | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-GORE | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-GOOR | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-GOGO | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-GOGR | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-GRRE | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-GROR | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-GRGO | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-GRGR | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-AQRE | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-AQOR | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-AQGO | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-AQGR | 20 (40 μL) | 200 μL |
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| LRP11-ULBP2-20-AQAQ | 20 (40 μL) | 200 μL |
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ULBP2 Gene Summary
This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq, Jul 2015]
Gene Name: UL16 Binding Protein 2
Chromosome: CHR6: 150263135 -150270368
Locus: 6q25.1
LRP11 Gene Summary
The LDL Receptor Related Protein 11 (LRP11) gene is located on chr6 :150139893-150185480 at 6q25.1.
Gene Name: LDL Receptor Related Protein 11
Chromosome: CHR6: 150139893 -150185480
Locus: 6q25.1
Gene Diseases
The LRP11 ULBP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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