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LRP6-GPR19 Fusion FISH Probe

The LRP6-GPR19 Fusion FISH Probe is used to confirm a fusion of the LRP6 and GPR19 genes. The fusion of the LRP6 and GPR19 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
LRP6-GPR19-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
LRP6-GPR19-20-RERE 20 (40 μL) 200 μL
LRP6-GPR19-20-REOR 20 (40 μL) 200 μL
LRP6-GPR19-20-REGO 20 (40 μL) 200 μL
LRP6-GPR19-20-REGR 20 (40 μL) 200 μL
LRP6-GPR19-20-REAQ 20 (40 μL) 200 μL
LRP6-GPR19-20-ORRE 20 (40 μL) 200 μL
LRP6-GPR19-20-OROR 20 (40 μL) 200 μL
LRP6-GPR19-20-ORGO 20 (40 μL) 200 μL
LRP6-GPR19-20-ORAQ 20 (40 μL) 200 μL
LRP6-GPR19-20-GORE 20 (40 μL) 200 μL
LRP6-GPR19-20-GOOR 20 (40 μL) 200 μL
LRP6-GPR19-20-GOGO 20 (40 μL) 200 μL
LRP6-GPR19-20-GOGR 20 (40 μL) 200 μL
LRP6-GPR19-20-GOAQ 20 (40 μL) 200 μL
LRP6-GPR19-20-GRRE 20 (40 μL) 200 μL
LRP6-GPR19-20-GROR 20 (40 μL) 200 μL
LRP6-GPR19-20-GRGO 20 (40 μL) 200 μL
LRP6-GPR19-20-GRGR 20 (40 μL) 200 μL
LRP6-GPR19-20-GRAQ 20 (40 μL) 200 μL
LRP6-GPR19-20-AQRE 20 (40 μL) 200 μL
LRP6-GPR19-20-AQOR 20 (40 μL) 200 μL
LRP6-GPR19-20-AQGO 20 (40 μL) 200 μL
LRP6-GPR19-20-AQGR 20 (40 μL) 200 μL
LRP6-GPR19-20-AQAQ 20 (40 μL) 200 μL

GPR19 Gene Summary

The G Protein-coupled Receptor 19 (GPR19) gene is located on chr12 :12813994-12849121 at 12p13.1.

Gene Name: G Protein-coupled Receptor 19

Chromosome: CHR12: 12813994 -12849121

Locus: 12p13.1

LRP6 Gene Summary

This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009]

Gene Name: LDL Receptor Related Protein 6

Chromosome: CHR12: 12268960 -12419811

Locus: 12p13.2

Gene Diseases

The LRP6 GPR19 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.