MAP2K4-DNAH9 Fusion FISH Probe
The MAP2K4-DNAH9 Fusion FISH Probe is used to confirm a fusion of the MAP2K4 and DNAH9 genes. The fusion of the MAP2K4 and DNAH9 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP2K4-DNAH9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-RERE | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-REOR | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-REGO | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-REGR | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-OROR | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-GORE | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-GROR | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP2K4-DNAH9-20-AQAQ | 20 (40 μL) | 200 μL |
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DNAH9 Gene Summary
This gene encodes the heavy chain subunit of axonemal dynein, a large multi-subunit molecular motor. Axonemal dynein attaches to microtubules and hydrolyzes ATP to mediate the movement of cilia and flagella. The gene expresses at least two transcript variants; additional variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Dynein Axonemal Heavy Chain 9
Chromosome: CHR17: 11501747 -11873065
Locus: 17p12
MAP2K4 Gene Summary
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Mitogen-activated Protein Kinase Kinase 4
Chromosome: CHR17: 11924134 -12047051
Locus: 17p12
Gene Diseases
The MAP2K4 DNAH9 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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