MAP3K1-OR4N2 Fusion FISH Probe
The MAP3K1-OR4N2 Fusion FISH Probe is used to confirm a fusion of the MAP3K1 and OR4N2 genes. The fusion of the MAP3K1 and OR4N2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP3K1-OR4N2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-RERE | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-REOR | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-REGO | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-REGR | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-OROR | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-GORE | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-GROR | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP3K1-OR4N2-20-AQAQ | 20 (40 μL) | 200 μL |
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MAP3K1 Gene Summary
The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012]
Gene Name: Mitogen-activated Protein Kinase Kinase Kinase 1
Chromosome: CHR5: 56110899 -56191978
Locus: 5q11.2
OR4N2 Gene Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a seven-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Mar 2014]
Gene Name: Olfactory Receptor Family 4 Subfamily N Member 2
Chromosome: CHR14: 20295607 -20296531
Locus: 14q11.2
Gene Diseases
The MAP3K1 OR4N2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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