MAP3K14-ACBD4 Fusion FISH Probe
The MAP3K14-ACBD4 Fusion FISH Probe is used to confirm a fusion of the MAP3K14 and ACBD4 genes. The fusion of the MAP3K14 and ACBD4 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP3K14-ACBD4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-RERE | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-REOR | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-REGO | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-REGR | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-OROR | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-GORE | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-GROR | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP3K14-ACBD4-20-AQAQ | 20 (40 μL) | 200 μL |
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MAP3K14 Gene Summary
This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]
Gene Name: Mitogen-activated Protein Kinase Kinase Kinase 14
Chromosome: CHR17: 43340487 -43394414
Locus: 17q21.31
ACBD4 Gene Summary
This gene encodes a member of the acyl-coenzyme A binding domain containing protein family. All family members contain the conserved acyl-Coenzyme A binding domain, which binds acyl-CoA thiol esters. They are thought to play roles in acyl-CoA dependent lipid metabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Gene Name: Acyl-CoA Binding Domain Containing 4
Chromosome: CHR17: 43209966 -43221543
Locus: 17q21.31
Gene Diseases
The MAP3K14 ACBD4 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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