MAP3K8-HEATR7B2 Fusion FISH Probe
The MAP3K8-HEATR7B2 Fusion FISH Probe is used to confirm a fusion of the MAP3K8 and HEATR7B2 genes. The fusion of the MAP3K8 and HEATR7B2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP3K8-HEATR7B2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-RERE | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-REOR | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-REGO | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-REGR | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-OROR | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-GORE | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-GROR | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP3K8-HEATR7B2-20-AQAQ | 20 (40 μL) | 200 μL |
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MAP3K8 Gene Summary
This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
Gene Name: Mitogen-activated Protein Kinase Kinase Kinase 8
Chromosome: CHR10: 30722949 -30750762
Locus: 10p11.23
Gene Diseases
The MAP3K8 HEATR7B2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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