MAPK12-SSTR3 Fusion FISH Probe
The MAPK12-SSTR3 Fusion FISH Probe is used to confirm a fusion of the MAPK12 and SSTR3 genes. The fusion of the MAPK12 and SSTR3 genes has been associated with Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAPK12-SSTR3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MAPK12-SSTR3-20-AQAQ | 20 (40 μL) | 200 μL |
|
MAPK12 Gene Summary
Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes. [provided by RefSeq, Jul 2008]
Gene Name: Mitogen-activated Protein Kinase 12
Chromosome: CHR22: 50691330 -50700089
Locus: 22q13.33
SSTR3 Gene Summary
This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Somatostatin Receptor 3
Chromosome: CHR22: 37602244 -37608353
Locus: 22q13.1
Gene Diseases
The MAPK12 SSTR3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|