SEARCH OUR PRODUCT CATALOG

MDM1-RBMS2 Fusion FISH Probe

The MDM1-RBMS2 Fusion FISH Probe is used to confirm a fusion of the MDM1 and RBMS2 genes. The fusion of the MDM1 and RBMS2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MDM1-RBMS2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MDM1-RBMS2-20-RERE 20 (40 μL) 200 μL
MDM1-RBMS2-20-REOR 20 (40 μL) 200 μL
MDM1-RBMS2-20-REGO 20 (40 μL) 200 μL
MDM1-RBMS2-20-REGR 20 (40 μL) 200 μL
MDM1-RBMS2-20-REAQ 20 (40 μL) 200 μL
MDM1-RBMS2-20-ORRE 20 (40 μL) 200 μL
MDM1-RBMS2-20-OROR 20 (40 μL) 200 μL
MDM1-RBMS2-20-ORGO 20 (40 μL) 200 μL
MDM1-RBMS2-20-ORAQ 20 (40 μL) 200 μL
MDM1-RBMS2-20-GORE 20 (40 μL) 200 μL
MDM1-RBMS2-20-GOOR 20 (40 μL) 200 μL
MDM1-RBMS2-20-GOGO 20 (40 μL) 200 μL
MDM1-RBMS2-20-GOGR 20 (40 μL) 200 μL
MDM1-RBMS2-20-GOAQ 20 (40 μL) 200 μL
MDM1-RBMS2-20-GRRE 20 (40 μL) 200 μL
MDM1-RBMS2-20-GROR 20 (40 μL) 200 μL
MDM1-RBMS2-20-GRGO 20 (40 μL) 200 μL
MDM1-RBMS2-20-GRGR 20 (40 μL) 200 μL
MDM1-RBMS2-20-GRAQ 20 (40 μL) 200 μL
MDM1-RBMS2-20-AQRE 20 (40 μL) 200 μL
MDM1-RBMS2-20-AQOR 20 (40 μL) 200 μL
MDM1-RBMS2-20-AQGO 20 (40 μL) 200 μL
MDM1-RBMS2-20-AQGR 20 (40 μL) 200 μL
MDM1-RBMS2-20-AQAQ 20 (40 μL) 200 μL

RBMS2 Gene Summary

The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. This protein was isolated by phenotypic complementation of cdc2 and cdc13 mutants of yeast and is thought to suppress cdc2 and cdc13 mutants through the induction of translation of cdc2. [provided by RefSeq, Jul 2008]

Gene Name: RNA Binding Motif Single Stranded Interacting Protein 2

Chromosome: CHR12: 56915608 -56989980

Locus: 12q13.3

MDM1 Gene Summary

This gene encodes a microtubule-binding nuclear protein that localizes to the centrioles of dividing cells and differentiating multiciliated cells, and negatively regulates centriole duplication. The encoded protein is closely associated with the centriole barrel, and resides in the centriole lumen. naturally occurring mutations in the orthologous mouse gene are associated with age-related retinal degeneration. [provided by RefSeq, Aug 2017]

Gene Name: Mdm1 Nuclear Protein

Chromosome: CHR12: 68688345 -68726161

Locus: 12q15

Gene Diseases

The MDM1 RBMS2 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.