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MECOM-LRRC34 Fusion FISH Probe

The MECOM-LRRC34 Fusion FISH Probe is used to confirm a fusion of the MECOM and LRRC34 genes. The fusion of the MECOM and LRRC34 genes has been associated with Uterine Corpus Endometrial Carcinoma, and Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MECOM-LRRC34-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MECOM-LRRC34-20-RERE 20 (40 μL) 200 μL
MECOM-LRRC34-20-REOR 20 (40 μL) 200 μL
MECOM-LRRC34-20-REGO 20 (40 μL) 200 μL
MECOM-LRRC34-20-REGR 20 (40 μL) 200 μL
MECOM-LRRC34-20-REAQ 20 (40 μL) 200 μL
MECOM-LRRC34-20-ORRE 20 (40 μL) 200 μL
MECOM-LRRC34-20-OROR 20 (40 μL) 200 μL
MECOM-LRRC34-20-ORGO 20 (40 μL) 200 μL
MECOM-LRRC34-20-ORAQ 20 (40 μL) 200 μL
MECOM-LRRC34-20-GORE 20 (40 μL) 200 μL
MECOM-LRRC34-20-GOOR 20 (40 μL) 200 μL
MECOM-LRRC34-20-GOGO 20 (40 μL) 200 μL
MECOM-LRRC34-20-GOGR 20 (40 μL) 200 μL
MECOM-LRRC34-20-GOAQ 20 (40 μL) 200 μL
MECOM-LRRC34-20-GRRE 20 (40 μL) 200 μL
MECOM-LRRC34-20-GROR 20 (40 μL) 200 μL
MECOM-LRRC34-20-GRGO 20 (40 μL) 200 μL
MECOM-LRRC34-20-GRGR 20 (40 μL) 200 μL
MECOM-LRRC34-20-GRAQ 20 (40 μL) 200 μL
MECOM-LRRC34-20-AQRE 20 (40 μL) 200 μL
MECOM-LRRC34-20-AQOR 20 (40 μL) 200 μL
MECOM-LRRC34-20-AQGO 20 (40 μL) 200 μL
MECOM-LRRC34-20-AQGR 20 (40 μL) 200 μL
MECOM-LRRC34-20-AQAQ 20 (40 μL) 200 μL

MECOM Gene Summary

The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

Gene Name: MDS1 And EVI1 Complex Locus

Chromosome: CHR3: 168801286 -169381563

Locus: 3q26.2

LRRC34 Gene Summary

The Leucine Rich Repeat Containing 34 (LRRC34) gene is located on chr3 :169511215-169530574 at 3q26.2.

Gene Name: Leucine Rich Repeat Containing 34

Chromosome: CHR3: 169511215 -169530574

Locus: 3q26.2

Gene Diseases

The MECOM LRRC34 Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma
Stomach Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.