MED1-EYS Fusion FISH Probe
The MED1-EYS Fusion FISH Probe is used to confirm a fusion of the MED1 and EYS genes. The fusion of the MED1 and EYS genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MED1-EYS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-RERE | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-REOR | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-REGO | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-REGR | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-REAQ | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-ORRE | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-OROR | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-ORGO | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-ORAQ | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-GORE | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-GOOR | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-GOGO | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-GOGR | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-GOAQ | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-GRRE | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-GROR | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-GRGO | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-GRGR | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-GRAQ | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-AQRE | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-AQOR | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-AQGO | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-AQGR | 20 (40 μL) | 200 μL |
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| MED1-EYS-20-AQAQ | 20 (40 μL) | 200 μL |
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MED1 Gene Summary
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008]
Gene Name: Mediator Complex Subunit 1
Chromosome: CHR17: 37560537 -37607527
Locus: 17q12
EYS Gene Summary
The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains. The protein is expressed in the photoreceptor layer of the retina, and the gene is mutated in autosomal recessive retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Name: Eyes Shut Homolog (Drosophila)
Chromosome: CHR6: 64429875 -66417118
Locus: 6q12
Gene Diseases
The MED1 EYS Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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