MED13L-MYBPC1 Fusion FISH Probe
The MED13L-MYBPC1 Fusion FISH Probe is used to confirm a fusion of the MED13L and MYBPC1 genes. The fusion of the MED13L and MYBPC1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MED13L-MYBPC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MED13L-MYBPC1-20-AQAQ | 20 (40 μL) | 200 μL |
|
MYBPC1 Gene Summary
This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Myosin Binding Protein C, Slow Type
Chromosome: CHR12: 101988746 -102079658
Locus: 12q23.2
MED13L Gene Summary
The protein encoded by this gene is a subunit of the Mediator complex, a large complex of proteins that functions as a transcriptional coactivator for most RNA polymerase II-transcribed genes. The encoded protein is involved in early development of the heart and brain. Defects in this gene are a cause of transposition of the great arteries, dextro-looped (DTGA).[provided by RefSeq, Jul 2010]
Gene Name: Mediator Complex Subunit 13 Like
Chromosome: CHR12: 116396380 -116714991
Locus: 12q24.21
Gene Diseases
The MED13L MYBPC1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|