MED25-ST8SIA6 Fusion FISH Probe
The MED25-ST8SIA6 Fusion FISH Probe is used to confirm a fusion of the MED25 and ST8SIA6 genes. The fusion of the MED25 and ST8SIA6 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MED25-ST8SIA6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-RERE | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-REOR | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-REGO | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-REGR | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-REAQ | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-ORRE | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-OROR | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-ORGO | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-ORAQ | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-GORE | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-GOOR | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-GOGO | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-GOGR | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-GOAQ | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-GRRE | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-GROR | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-GRGO | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-GRGR | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-GRAQ | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-AQRE | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-AQOR | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-AQGO | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-AQGR | 20 (40 μL) | 200 μL |
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| MED25-ST8SIA6-20-AQAQ | 20 (40 μL) | 200 μL |
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MED25 Gene Summary
This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq, Apr 2010]
Gene Name: Mediator Complex Subunit 25
Chromosome: CHR19: 50321535 -50340237
Locus: 19q13.33
ST8SIA6 Gene Summary
This gene encodes a member of the glycosyltransferase 29 protein family. Members of this protein family synthesize sialylglycoconjugates. Sialylation may contribute to multidrug resistance in cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Gene Name: ST8 Alpha-N-acetyl-neuraminide Alpha-2,8-sialyltransferase 6
Chromosome: CHR10: 17362675 -17496254
Locus: 10p12.33
Gene Diseases
The MED25 ST8SIA6 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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