MELK-CNTFR Fusion FISH Probe
The MELK-CNTFR Fusion FISH Probe is used to confirm a fusion of the MELK and CNTFR genes. The fusion of the MELK and CNTFR genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MELK-CNTFR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-RERE | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-REOR | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-REGO | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-REGR | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-REAQ | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-ORRE | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-OROR | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-ORGO | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-ORAQ | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-GORE | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-GOOR | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-GOGO | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-GOGR | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-GOAQ | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-GRRE | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-GROR | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-GRGO | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-GRGR | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-GRAQ | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-AQRE | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-AQOR | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-AQGO | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-AQGR | 20 (40 μL) | 200 μL |
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| MELK-CNTFR-20-AQAQ | 20 (40 μL) | 200 μL |
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CNTFR Gene Summary
This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]
Gene Name: Ciliary Neurotrophic Factor Receptor
Chromosome: CHR9: 34551429 -34590138
Locus: 9p13.3
MELK Gene Summary
The Maternal Embryonic Leucine Zipper Kinase (MELK) gene is located on chr9 :36572904-36677679 at 9p13.2.
Gene Name: Maternal Embryonic Leucine Zipper Kinase
Chromosome: CHR9: 36572904 -36677679
Locus: 9p13.2
Gene Diseases
The MELK CNTFR Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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