MGAT5B-CYP11A1 Fusion FISH Probe
The MGAT5B-CYP11A1 Fusion FISH Probe is used to confirm a fusion of the MGAT5B and CYP11A1 genes. The fusion of the MGAT5B and CYP11A1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MGAT5B-CYP11A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-RERE | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-REOR | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-REGO | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-REGR | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-REAQ | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-ORRE | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-OROR | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-ORGO | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-GORE | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-GOOR | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-GOGO | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-GOGR | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-GRRE | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-GROR | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-GRGO | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-GRGR | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-AQRE | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-AQOR | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-AQGO | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-AQGR | 20 (40 μL) | 200 μL |
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| MGAT5B-CYP11A1-20-AQAQ | 20 (40 μL) | 200 μL |
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CYP11A1 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]
Gene Name: Cytochrome P450 Family 11 Subfamily A Member 1
Chromosome: CHR15: 74630102 -74660081
Locus: 15q24.1
MGAT5B Gene Summary
The MGAT5B gene encodes a beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.155) that functions in the synthesis of complex cell surface N-glycans (Kaneko et al., 2003 [PubMed 14623122]).[supplied by OMIM, Nov 2008]
Gene Name: Mannosyl (alpha-1,6-)-glycoprotein Beta-1,6-N-acetyl-glucosaminyltransferase, Isozyme B
Chromosome: CHR17: 74864797 -74946471
Locus: 17q25.2
Gene Diseases
The MGAT5B CYP11A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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