MICAL2-NELL1 Fusion FISH Probe
The MICAL2-NELL1 Fusion FISH Probe is used to confirm a fusion of the MICAL2 and NELL1 genes. The fusion of the MICAL2 and NELL1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MICAL2-NELL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-RERE | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-REOR | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-REGO | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-REGR | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-REAQ | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-ORRE | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-OROR | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-ORGO | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-GORE | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-GOOR | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-GOGO | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-GOGR | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-GRRE | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-GROR | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-GRGO | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-GRGR | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-AQRE | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-AQOR | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-AQGO | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-AQGR | 20 (40 μL) | 200 μL |
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| MICAL2-NELL1-20-AQAQ | 20 (40 μL) | 200 μL |
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NELL1 Gene Summary
This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Gene Name: Neural EGFL Like 1
Chromosome: CHR11: 20691116 -21597229
Locus: 11p15.1
MICAL2 Gene Summary
The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]
Gene Name: Microtubule Associated Monooxygenase, Calponin And LIM Domain Containing 2
Chromosome: CHR11: 12132137 -12285331
Locus: 11p15.3
Gene Diseases
The MICAL2 NELL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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