MLLT4-KCNAB1 Fusion FISH Probe
The MLLT4-KCNAB1 Fusion FISH Probe is used to confirm a fusion of the MLLT4 and KCNAB1 genes. The fusion of the MLLT4 and KCNAB1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MLLT4-KCNAB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-RERE | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-REOR | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-REGO | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-REGR | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-REAQ | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-ORRE | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-OROR | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-ORGO | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-GORE | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-GOOR | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-GOGO | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-GOGR | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-GRRE | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-GROR | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-GRGO | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-GRGR | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-AQRE | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-AQOR | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-AQGO | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-AQGR | 20 (40 μL) | 200 μL |
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| MLLT4-KCNAB1-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNAB1 Gene Summary
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Apr 2015]
Gene Name: Potassium Voltage-gated Channel Subfamily A Member Regulatory Beta Subunit 1
Chromosome: CHR3: 155838336 -156256927
Locus: 3q25.31
Gene Diseases
The MLLT4 KCNAB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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