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MLLT4-SASH1 Fusion FISH Probe

The MLLT4-SASH1 Fusion FISH Probe is used to confirm a fusion of the MLLT4 and SASH1 genes. The fusion of the MLLT4 and SASH1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MLLT4-SASH1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MLLT4-SASH1-20-RERE 20 (40 μL) 200 μL
MLLT4-SASH1-20-REOR 20 (40 μL) 200 μL
MLLT4-SASH1-20-REGO 20 (40 μL) 200 μL
MLLT4-SASH1-20-REGR 20 (40 μL) 200 μL
MLLT4-SASH1-20-REAQ 20 (40 μL) 200 μL
MLLT4-SASH1-20-ORRE 20 (40 μL) 200 μL
MLLT4-SASH1-20-OROR 20 (40 μL) 200 μL
MLLT4-SASH1-20-ORGO 20 (40 μL) 200 μL
MLLT4-SASH1-20-ORAQ 20 (40 μL) 200 μL
MLLT4-SASH1-20-GORE 20 (40 μL) 200 μL
MLLT4-SASH1-20-GOOR 20 (40 μL) 200 μL
MLLT4-SASH1-20-GOGO 20 (40 μL) 200 μL
MLLT4-SASH1-20-GOGR 20 (40 μL) 200 μL
MLLT4-SASH1-20-GOAQ 20 (40 μL) 200 μL
MLLT4-SASH1-20-GRRE 20 (40 μL) 200 μL
MLLT4-SASH1-20-GROR 20 (40 μL) 200 μL
MLLT4-SASH1-20-GRGO 20 (40 μL) 200 μL
MLLT4-SASH1-20-GRGR 20 (40 μL) 200 μL
MLLT4-SASH1-20-GRAQ 20 (40 μL) 200 μL
MLLT4-SASH1-20-AQRE 20 (40 μL) 200 μL
MLLT4-SASH1-20-AQOR 20 (40 μL) 200 μL
MLLT4-SASH1-20-AQGO 20 (40 μL) 200 μL
MLLT4-SASH1-20-AQGR 20 (40 μL) 200 μL
MLLT4-SASH1-20-AQAQ 20 (40 μL) 200 μL

SASH1 Gene Summary

This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients. [provided by RefSeq, Oct 2016]

Gene Name: SAM And SH3 Domain Containing 1

Chromosome: CHR6: 148663728 -148873184

Locus: 6q24.3-q25.1

Gene Diseases

The MLLT4 SASH1 Fusion has been associated with the following diseases:

Disease Name
Brain Lower Grade Glioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.