MMP11-GAS2L1 Fusion FISH Probe
The MMP11-GAS2L1 Fusion FISH Probe is used to confirm a fusion of the MMP11 and GAS2L1 genes. The fusion of the MMP11 and GAS2L1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MMP11-GAS2L1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-RERE | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-REOR | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-REGO | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-REGR | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-REAQ | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-ORRE | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-OROR | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-ORGO | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-GORE | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-GOOR | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-GOGO | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-GOGR | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-GRRE | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-GROR | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-GRGO | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-GRGR | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-AQRE | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-AQOR | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-AQGO | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-AQGR | 20 (40 μL) | 200 μL |
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| MMP11-GAS2L1-20-AQAQ | 20 (40 μL) | 200 μL |
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MMP11 Gene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]
Gene Name: Matrix Metallopeptidase 11
Chromosome: CHR22: 24115035 -24126503
Locus: 22q11.23
GAS2L1 Gene Summary
This gene encodes a member of the growth arrest-specific 2 protein family. This protein binds components of the cytoskeleton and may be involved in mediating interactions between microtubules and microfilaments. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Jul 2013]
Gene Name: Growth Arrest Specific 2 Like 1
Chromosome: CHR22: 29702996 -29708774
Locus: 22q12.2
Gene Diseases
The MMP11 GAS2L1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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