MMP26-GUCY2F Fusion FISH Probe
The MMP26-GUCY2F Fusion FISH Probe is used to confirm a fusion of the MMP26 and GUCY2F genes. The fusion of the MMP26 and GUCY2F genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MMP26-GUCY2F-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-RERE | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-REOR | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-REGO | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-REGR | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-REAQ | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-ORRE | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-OROR | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-ORGO | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-ORAQ | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-GORE | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-GOOR | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-GOGO | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-GOGR | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-GOAQ | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-GRRE | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-GROR | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-GRGO | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-GRGR | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-GRAQ | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-AQRE | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-AQOR | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-AQGO | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-AQGR | 20 (40 μL) | 200 μL |
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| MMP26-GUCY2F-20-AQAQ | 20 (40 μL) | 200 μL |
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GUCY2F Gene Summary
The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa. [provided by RefSeq, Dec 2008]
Gene Name: Guanylate Cyclase 2F, Retinal
Chromosome: CHRX: 108616134 -108725285
Locus: Xq22.3-q23
MMP26 Gene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme may degrade collagen type IV, fibronectin, fibrinogen, and beta-casein, and activate matrix metalloproteinase-9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The encoded protein may promote cell invasion in multiple human cancers. [provided by RefSeq, May 2016]
Gene Name: Matrix Metallopeptidase 26
Chromosome: CHR11: 5009423 -5013659
Locus: 11p15.4
Gene Diseases
The MMP26 GUCY2F Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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