MMP9-UTRN Fusion FISH Probe
The MMP9-UTRN Fusion FISH Probe is used to confirm a fusion of the MMP9 and UTRN genes. The fusion of the MMP9 and UTRN genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MMP9-UTRN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MMP9-UTRN-20-AQAQ | 20 (40 μL) | 200 μL |
|
MMP9 Gene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
Gene Name: Matrix Metallopeptidase 9
Chromosome: CHR20: 44637546 -44645200
Locus: 20q13.12
UTRN Gene Summary
This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
Gene Name: Utrophin
Chromosome: CHR6: 144612872 -145174170
Locus: 6q24.2
Gene Diseases
The MMP9 UTRN Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|