MMS19-MICU1 Fusion FISH Probe
The MMS19-MICU1 Fusion FISH Probe is used to confirm a fusion of the MMS19 and MICU1 genes. The fusion of the MMS19 and MICU1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MMS19-MICU1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-RERE | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-REOR | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-REGO | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-REGR | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-REAQ | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-ORRE | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-OROR | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-ORGO | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-GORE | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-GOOR | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-GOGO | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-GOGR | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-GRRE | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-GROR | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-GRGO | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-GRGR | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-AQRE | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-AQOR | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-AQGO | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-AQGR | 20 (40 μL) | 200 μL |
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| MMS19-MICU1-20-AQAQ | 20 (40 μL) | 200 μL |
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MICU1 Gene Summary
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]
Gene Name: Mitochondrial Calcium Uptake 1
Chromosome: CHR10: 74127083 -74385949
Locus: 10q22.1
MMS19 Gene Summary
The MMS19 Homolog, Cytosolic Iron-sulfur Assembly Component (MMS19) gene is located on chr10 :99218080-99258366 at 10q24.1.
Gene Name: MMS19 Homolog, Cytosolic Iron-sulfur Assembly Component
Chromosome: CHR10: 99218080 -99258366
Locus: 10q24.1
Gene Diseases
The MMS19 MICU1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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