MPO-ANXA1 Fusion FISH Probe
The MPO-ANXA1 Fusion FISH Probe is used to confirm a fusion of the MPO and ANXA1 genes. The fusion of the MPO and ANXA1 genes has been associated with Acute Myeloid Leukemia. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MPO-ANXA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-RERE | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-REOR | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-REGO | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-REGR | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-REAQ | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-ORRE | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-OROR | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-ORGO | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-GORE | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-GOOR | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-GOGO | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-GOGR | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-GRRE | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-GROR | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-GRGO | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-GRGR | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-AQRE | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-AQOR | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-AQGO | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-AQGR | 20 (40 μL) | 200 μL |
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| MPO-ANXA1-20-AQAQ | 20 (40 μL) | 200 μL |
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ANXA1 Gene Summary
This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]
Gene Name: Annexin A1
Chromosome: CHR9: 75766780 -75785307
Locus: 9q21.13
MPO Gene Summary
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]
Gene Name: Myeloperoxidase
Chromosome: CHR17: 56347216 -56358296
Locus: 17q22
Gene Diseases
The MPO ANXA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Acute Myeloid Leukemia |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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