MRC2-RND2 Fusion FISH Probe
The MRC2-RND2 Fusion FISH Probe is used to confirm a fusion of the MRC2 and RND2 genes. The fusion of the MRC2 and RND2 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MRC2-RND2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MRC2-RND2-20-AQAQ | 20 (40 μL) | 200 μL |
|
RND2 Gene Summary
This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1. [provided by RefSeq, Jul 2008]
Gene Name: Rho Family GTPase 2
Chromosome: CHR17: 41177257 -41184058
Locus: 17q21.31
MRC2 Gene Summary
This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012]
Gene Name: Mannose Receptor C Type 2
Chromosome: CHR17: 60704761 -60770952
Locus: 17q23.2
Gene Diseases
The MRC2 RND2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|