MREG-SMARCAL1 Fusion FISH Probe
The MREG-SMARCAL1 Fusion FISH Probe is used to confirm a fusion of the MREG and SMARCAL1 genes. The fusion of the MREG and SMARCAL1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MREG-SMARCAL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-RERE | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-REOR | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-REGO | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-REGR | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-REAQ | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-ORRE | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-OROR | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-ORGO | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-GORE | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-GOOR | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-GOGO | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-GOGR | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-GRRE | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-GROR | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-GRGO | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-GRGR | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-AQRE | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-AQOR | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-AQGO | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-AQGR | 20 (40 μL) | 200 μL |
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| MREG-SMARCAL1-20-AQAQ | 20 (40 μL) | 200 μL |
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SMARCAL1 Gene Summary
The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency. [provided by RefSeq, Jul 2008]
Gene Name: SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like 1
Chromosome: CHR2: 217277136 -217347774
Locus: 2q35
MREG Gene Summary
The Melanoregulin (MREG) gene is located on chr2 :216807313-216878346 at 2q35.
Gene Name: Melanoregulin
Chromosome: CHR2: 216807313 -216878346
Locus: 2q35
Gene Diseases
The MREG SMARCAL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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