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MRPS35-LYRM5 Fusion FISH Probe

The MRPS35-LYRM5 Fusion FISH Probe is used to confirm a fusion of the MRPS35 and LYRM5 genes. The fusion of the MRPS35 and LYRM5 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MRPS35-LYRM5-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MRPS35-LYRM5-20-RERE 20 (40 μL) 200 μL
MRPS35-LYRM5-20-REOR 20 (40 μL) 200 μL
MRPS35-LYRM5-20-REGO 20 (40 μL) 200 μL
MRPS35-LYRM5-20-REGR 20 (40 μL) 200 μL
MRPS35-LYRM5-20-REAQ 20 (40 μL) 200 μL
MRPS35-LYRM5-20-ORRE 20 (40 μL) 200 μL
MRPS35-LYRM5-20-OROR 20 (40 μL) 200 μL
MRPS35-LYRM5-20-ORGO 20 (40 μL) 200 μL
MRPS35-LYRM5-20-ORAQ 20 (40 μL) 200 μL
MRPS35-LYRM5-20-GORE 20 (40 μL) 200 μL
MRPS35-LYRM5-20-GOOR 20 (40 μL) 200 μL
MRPS35-LYRM5-20-GOGO 20 (40 μL) 200 μL
MRPS35-LYRM5-20-GOGR 20 (40 μL) 200 μL
MRPS35-LYRM5-20-GOAQ 20 (40 μL) 200 μL
MRPS35-LYRM5-20-GRRE 20 (40 μL) 200 μL
MRPS35-LYRM5-20-GROR 20 (40 μL) 200 μL
MRPS35-LYRM5-20-GRGO 20 (40 μL) 200 μL
MRPS35-LYRM5-20-GRGR 20 (40 μL) 200 μL
MRPS35-LYRM5-20-GRAQ 20 (40 μL) 200 μL
MRPS35-LYRM5-20-AQRE 20 (40 μL) 200 μL
MRPS35-LYRM5-20-AQOR 20 (40 μL) 200 μL
MRPS35-LYRM5-20-AQGO 20 (40 μL) 200 μL
MRPS35-LYRM5-20-AQGR 20 (40 μL) 200 μL
MRPS35-LYRM5-20-AQAQ 20 (40 μL) 200 μL

MRPS35 Gene Summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has had confusing nomenclature in the literature. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 3p, 5q, and 10q. [provided by RefSeq, Jul 2010]

Gene Name: Mitochondrial Ribosomal Protein S35

Chromosome: CHR12: 27863705 -27909237

Locus: 12p11.22

Gene Diseases

The MRPS35 LYRM5 Fusion has been associated with the following diseases:

Disease Name
Stomach Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.