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MSH2-EPCAM Fusion FISH Probe

The MSH2-EPCAM Fusion FISH Probe is used to confirm a fusion of the MSH2 and EPCAM genes. The fusion of the MSH2 and EPCAM genes has been associated with Stomach Adenocarcinoma, and Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MSH2-EPCAM-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MSH2-EPCAM-20-RERE 20 (40 μL) 200 μL
MSH2-EPCAM-20-REOR 20 (40 μL) 200 μL
MSH2-EPCAM-20-REGO 20 (40 μL) 200 μL
MSH2-EPCAM-20-REGR 20 (40 μL) 200 μL
MSH2-EPCAM-20-REAQ 20 (40 μL) 200 μL
MSH2-EPCAM-20-ORRE 20 (40 μL) 200 μL
MSH2-EPCAM-20-OROR 20 (40 μL) 200 μL
MSH2-EPCAM-20-ORGO 20 (40 μL) 200 μL
MSH2-EPCAM-20-ORAQ 20 (40 μL) 200 μL
MSH2-EPCAM-20-GORE 20 (40 μL) 200 μL
MSH2-EPCAM-20-GOOR 20 (40 μL) 200 μL
MSH2-EPCAM-20-GOGO 20 (40 μL) 200 μL
MSH2-EPCAM-20-GOGR 20 (40 μL) 200 μL
MSH2-EPCAM-20-GOAQ 20 (40 μL) 200 μL
MSH2-EPCAM-20-GRRE 20 (40 μL) 200 μL
MSH2-EPCAM-20-GROR 20 (40 μL) 200 μL
MSH2-EPCAM-20-GRGO 20 (40 μL) 200 μL
MSH2-EPCAM-20-GRGR 20 (40 μL) 200 μL
MSH2-EPCAM-20-GRAQ 20 (40 μL) 200 μL
MSH2-EPCAM-20-AQRE 20 (40 μL) 200 μL
MSH2-EPCAM-20-AQOR 20 (40 μL) 200 μL
MSH2-EPCAM-20-AQGO 20 (40 μL) 200 μL
MSH2-EPCAM-20-AQGR 20 (40 μL) 200 μL
MSH2-EPCAM-20-AQAQ 20 (40 μL) 200 μL

EPCAM Gene Summary

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]

Gene Name: Epithelial Cell Adhesion Molecule

Chromosome: CHR2: 47596286 -47614167

Locus: 2p21

MSH2 Gene Summary

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Gene Name: MutS Homolog 2

Chromosome: CHR2: 47630262 -47710360

Locus: 2p21-p16.3

Gene Diseases

The MSH2 EPCAM Fusion has been associated with the following diseases:

Disease Name
Stomach Adenocarcinoma
Esophageal Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.