MSH2-SLC3A1 Fusion FISH Probe
The MSH2-SLC3A1 Fusion FISH Probe is used to confirm a fusion of the MSH2 and SLC3A1 genes. The fusion of the MSH2 and SLC3A1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MSH2-SLC3A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-RERE | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-REOR | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-REGO | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-REGR | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-REAQ | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-ORRE | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-OROR | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-ORGO | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-GORE | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-GOOR | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-GOGO | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-GOGR | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-GRRE | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-GROR | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-GRGO | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-GRGR | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-AQRE | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-AQOR | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-AQGO | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-AQGR | 20 (40 μL) | 200 μL |
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| MSH2-SLC3A1-20-AQAQ | 20 (40 μL) | 200 μL |
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MSH2 Gene Summary
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Name: MutS Homolog 2
Chromosome: CHR2: 47630262 -47710360
Locus: 2p21-p16.3
SLC3A1 Gene Summary
This gene encodes a type II membrane glycoprotein which is one of the components of the renal amino acid transporter which transports neutral and basic amino acids in the renal tubule and intestinal tract. Mutations and deletions in this gene are associated with cystinuria. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Solute Carrier Family 3 Member 1
Chromosome: CHR2: 44502596 -44547962
Locus: 2p21
Gene Diseases
The MSH2 SLC3A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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