MSI2-AKAP1 Fusion FISH Probe
The MSI2-AKAP1 Fusion FISH Probe is used to confirm a fusion of the MSI2 and AKAP1 genes. The fusion of the MSI2 and AKAP1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MSI2-AKAP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-RERE | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-REOR | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-REGO | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-REGR | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-REAQ | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-ORRE | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-OROR | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-ORGO | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-GORE | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-GOOR | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-GOGO | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-GOGR | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-GRRE | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-GROR | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-GRGO | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-GRGR | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-AQRE | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-AQOR | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-AQGO | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-AQGR | 20 (40 μL) | 200 μL |
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| MSI2-AKAP1-20-AQAQ | 20 (40 μL) | 200 μL |
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AKAP1 Gene Summary
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment. [provided by RefSeq, Jul 2008]
Gene Name: A-kinase Anchoring Protein 1
Chromosome: CHR17: 55162552 -55198710
Locus: 17q22
MSI2 Gene Summary
This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016]
Gene Name: Musashi RNA Binding Protein 2
Chromosome: CHR17: 55333930 -55757299
Locus: 17q22
Gene Diseases
The MSI2 AKAP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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