MSMB-SUPT16H Fusion FISH Probe
The MSMB-SUPT16H Fusion FISH Probe is used to confirm a fusion of the MSMB and SUPT16H genes. The fusion of the MSMB and SUPT16H genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MSMB-SUPT16H-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-RERE | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-REOR | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-REGO | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-REGR | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-REAQ | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-ORRE | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-OROR | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-ORGO | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-ORAQ | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-GORE | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-GOOR | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-GOGO | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-GOGR | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-GOAQ | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-GRRE | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-GROR | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-GRGO | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-GRGR | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-GRAQ | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-AQRE | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-AQOR | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-AQGO | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-AQGR | 20 (40 μL) | 200 μL |
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| MSMB-SUPT16H-20-AQAQ | 20 (40 μL) | 200 μL |
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MSMB Gene Summary
The protein encoded by this gene is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding different isoforms are described for this gene. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Microseminoprotein Beta
Chromosome: CHR10: 51549552 -51562518
Locus: 10q11.22
SUPT16H Gene Summary
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009]
Gene Name: SPT16 Homolog, Facilitates Chromatin Remodeling Subunit
Chromosome: CHR14: 21819630 -21852425
Locus: 14q11.2
Gene Diseases
The MSMB SUPT16H Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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