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MSN-NLRC4 Fusion FISH Probe

The MSN-NLRC4 Fusion FISH Probe is used to confirm a fusion of the MSN and NLRC4 genes. The fusion of the MSN and NLRC4 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MSN-NLRC4-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MSN-NLRC4-20-RERE 20 (40 μL) 200 μL
MSN-NLRC4-20-REOR 20 (40 μL) 200 μL
MSN-NLRC4-20-REGO 20 (40 μL) 200 μL
MSN-NLRC4-20-REGR 20 (40 μL) 200 μL
MSN-NLRC4-20-REAQ 20 (40 μL) 200 μL
MSN-NLRC4-20-ORRE 20 (40 μL) 200 μL
MSN-NLRC4-20-OROR 20 (40 μL) 200 μL
MSN-NLRC4-20-ORGO 20 (40 μL) 200 μL
MSN-NLRC4-20-ORAQ 20 (40 μL) 200 μL
MSN-NLRC4-20-GORE 20 (40 μL) 200 μL
MSN-NLRC4-20-GOOR 20 (40 μL) 200 μL
MSN-NLRC4-20-GOGO 20 (40 μL) 200 μL
MSN-NLRC4-20-GOGR 20 (40 μL) 200 μL
MSN-NLRC4-20-GOAQ 20 (40 μL) 200 μL
MSN-NLRC4-20-GRRE 20 (40 μL) 200 μL
MSN-NLRC4-20-GROR 20 (40 μL) 200 μL
MSN-NLRC4-20-GRGO 20 (40 μL) 200 μL
MSN-NLRC4-20-GRGR 20 (40 μL) 200 μL
MSN-NLRC4-20-GRAQ 20 (40 μL) 200 μL
MSN-NLRC4-20-AQRE 20 (40 μL) 200 μL
MSN-NLRC4-20-AQOR 20 (40 μL) 200 μL
MSN-NLRC4-20-AQGO 20 (40 μL) 200 μL
MSN-NLRC4-20-AQGR 20 (40 μL) 200 μL
MSN-NLRC4-20-AQAQ 20 (40 μL) 200 μL

MSN Gene Summary

Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008]

Gene Name: Moesin

Chromosome: CHRX: 64887510 -64961793

Locus: Xq12

NLRC4 Gene Summary

This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Gene Name: NLR Family CARD Domain Containing 4

Chromosome: CHR2: 32449517 -32490812

Locus: 2p22.3

Gene Diseases

The MSN NLRC4 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.