MSRB3-BCL2L14 Fusion FISH Probe
The MSRB3-BCL2L14 Fusion FISH Probe is used to confirm a fusion of the MSRB3 and BCL2L14 genes. The fusion of the MSRB3 and BCL2L14 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MSRB3-BCL2L14-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MSRB3-BCL2L14-20-AQAQ | 20 (40 μL) | 200 μL |
|
BCL2L14 Gene Summary
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009]
Gene Name: BCL2 Like 14
Chromosome: CHR12: 12223877 -12252627
Locus: 12p13.2
MSRB3 Gene Summary
The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. [provided by RefSeq, Jul 2010]
Gene Name: Methionine Sulfoxide Reductase B3
Chromosome: CHR12: 65672422 -65860687
Locus: 12q14.3
Gene Diseases
The MSRB3 BCL2L14 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|