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MTF1-SF3A3 Fusion FISH Probe

The MTF1-SF3A3 Fusion FISH Probe is used to confirm a fusion of the MTF1 and SF3A3 genes. The fusion of the MTF1 and SF3A3 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MTF1-SF3A3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MTF1-SF3A3-20-RERE 20 (40 μL) 200 μL
MTF1-SF3A3-20-REOR 20 (40 μL) 200 μL
MTF1-SF3A3-20-REGO 20 (40 μL) 200 μL
MTF1-SF3A3-20-REGR 20 (40 μL) 200 μL
MTF1-SF3A3-20-REAQ 20 (40 μL) 200 μL
MTF1-SF3A3-20-ORRE 20 (40 μL) 200 μL
MTF1-SF3A3-20-OROR 20 (40 μL) 200 μL
MTF1-SF3A3-20-ORGO 20 (40 μL) 200 μL
MTF1-SF3A3-20-ORAQ 20 (40 μL) 200 μL
MTF1-SF3A3-20-GORE 20 (40 μL) 200 μL
MTF1-SF3A3-20-GOOR 20 (40 μL) 200 μL
MTF1-SF3A3-20-GOGO 20 (40 μL) 200 μL
MTF1-SF3A3-20-GOGR 20 (40 μL) 200 μL
MTF1-SF3A3-20-GOAQ 20 (40 μL) 200 μL
MTF1-SF3A3-20-GRRE 20 (40 μL) 200 μL
MTF1-SF3A3-20-GROR 20 (40 μL) 200 μL
MTF1-SF3A3-20-GRGO 20 (40 μL) 200 μL
MTF1-SF3A3-20-GRGR 20 (40 μL) 200 μL
MTF1-SF3A3-20-GRAQ 20 (40 μL) 200 μL
MTF1-SF3A3-20-AQRE 20 (40 μL) 200 μL
MTF1-SF3A3-20-AQOR 20 (40 μL) 200 μL
MTF1-SF3A3-20-AQGO 20 (40 μL) 200 μL
MTF1-SF3A3-20-AQGR 20 (40 μL) 200 μL
MTF1-SF3A3-20-AQAQ 20 (40 μL) 200 μL

MTF1 Gene Summary

This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq, Jul 2008]

Gene Name: Metal Regulatory Transcription Factor 1

Chromosome: CHR1: 38275238 -38325292

Locus: 1p34.3

SF3A3 Gene Summary

This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Gene Name: Splicing Factor 3a Subunit 3

Chromosome: CHR1: 38422651 -38455761

Locus: 1p34.3

Gene Diseases

The MTF1 SF3A3 Fusion has been associated with the following diseases:

Disease Name
Glioblastoma Multiforme

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.