MTRR-NMD3 Fusion FISH Probe
The MTRR-NMD3 Fusion FISH Probe is used to confirm a fusion of the MTRR and NMD3 genes. The fusion of the MTRR and NMD3 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MTRR-NMD3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-RERE | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-REOR | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-REGO | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-REGR | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-REAQ | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-ORRE | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-OROR | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-ORGO | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-ORAQ | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-GORE | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-GOOR | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-GOGO | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-GOGR | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-GOAQ | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-GRRE | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-GROR | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-GRGO | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-GRGR | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-GRAQ | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-AQRE | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-AQOR | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-AQGO | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-AQGR | 20 (40 μL) | 200 μL |
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| MTRR-NMD3-20-AQAQ | 20 (40 μL) | 200 μL |
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MTRR Gene Summary
This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: 5-methyltetrahydrofolate-homocysteine Methyltransferase Reductase
Chromosome: CHR5: 7869216 -7901235
Locus: 5p15.31
NMD3 Gene Summary
Ribosomal 40S and 60S subunits associate in the nucleolus and are exported to the cytoplasm. The protein encoded by this gene is involved in the passage of the 60S subunit through the nuclear pore complex and into the cytoplasm. Several transcript variants exist for this gene, but the full-length natures of only two have been described to date. [provided by RefSeq, Feb 2016]
Gene Name: NMD3 Ribosome Export Adaptor
Chromosome: CHR3: 160939098 -160969795
Locus: 3q26.1
Gene Diseases
The MTRR NMD3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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