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MXI1-C10ORF57 Fusion FISH Probe

The MXI1-C10ORF57 Fusion FISH Probe is used to confirm a fusion of the MXI1 and C10ORF57 genes. The fusion of the MXI1 and C10ORF57 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MXI1-C10ORF57-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
MXI1-C10ORF57-20-RERE 20 (40 μL) 200 μL
MXI1-C10ORF57-20-REOR 20 (40 μL) 200 μL
MXI1-C10ORF57-20-REGO 20 (40 μL) 200 μL
MXI1-C10ORF57-20-REGR 20 (40 μL) 200 μL
MXI1-C10ORF57-20-REAQ 20 (40 μL) 200 μL
MXI1-C10ORF57-20-ORRE 20 (40 μL) 200 μL
MXI1-C10ORF57-20-OROR 20 (40 μL) 200 μL
MXI1-C10ORF57-20-ORGO 20 (40 μL) 200 μL
MXI1-C10ORF57-20-ORAQ 20 (40 μL) 200 μL
MXI1-C10ORF57-20-GORE 20 (40 μL) 200 μL
MXI1-C10ORF57-20-GOOR 20 (40 μL) 200 μL
MXI1-C10ORF57-20-GOGO 20 (40 μL) 200 μL
MXI1-C10ORF57-20-GOGR 20 (40 μL) 200 μL
MXI1-C10ORF57-20-GOAQ 20 (40 μL) 200 μL
MXI1-C10ORF57-20-GRRE 20 (40 μL) 200 μL
MXI1-C10ORF57-20-GROR 20 (40 μL) 200 μL
MXI1-C10ORF57-20-GRGO 20 (40 μL) 200 μL
MXI1-C10ORF57-20-GRGR 20 (40 μL) 200 μL
MXI1-C10ORF57-20-GRAQ 20 (40 μL) 200 μL
MXI1-C10ORF57-20-AQRE 20 (40 μL) 200 μL
MXI1-C10ORF57-20-AQOR 20 (40 μL) 200 μL
MXI1-C10ORF57-20-AQGO 20 (40 μL) 200 μL
MXI1-C10ORF57-20-AQGR 20 (40 μL) 200 μL
MXI1-C10ORF57-20-AQAQ 20 (40 μL) 200 μL

MXI1 Gene Summary

Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq, Jul 2008]

Gene Name: MAX Interactor 1, Dimerization Protein

Chromosome: CHR10: 111967362 -112047123

Locus: 10q25.2

Gene Diseases

The MXI1 C10ORF57 Fusion has been associated with the following diseases:

Disease Name
Colon Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.