MYBPC1-NPY Fusion FISH Probe
The MYBPC1-NPY Fusion FISH Probe is used to confirm a fusion of the MYBPC1 and NPY genes. The fusion of the MYBPC1 and NPY genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MYBPC1-NPY-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MYBPC1-NPY-20-AQAQ | 20 (40 μL) | 200 μL |
|
MYBPC1 Gene Summary
This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Myosin Binding Protein C, Slow Type
Chromosome: CHR12: 101988746 -102079658
Locus: 12q23.2
NPY Gene Summary
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
Gene Name: Neuropeptide Y
Chromosome: CHR7: 24323806 -24331484
Locus: 7p15.3
Gene Diseases
The MYBPC1 NPY Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|