MYH14-SIGLEC16 Fusion FISH Probe
The MYH14-SIGLEC16 Fusion FISH Probe is used to confirm a fusion of the MYH14 and SIGLEC16 genes. The fusion of the MYH14 and SIGLEC16 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MYH14-SIGLEC16-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-RERE | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-REOR | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-REGO | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-REGR | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-REAQ | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-ORRE | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-OROR | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-ORGO | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-ORAQ | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-GORE | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-GOOR | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-GOGO | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-GOGR | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-GOAQ | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-GRRE | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-GROR | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-GRGO | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-GRGR | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-GRAQ | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-AQRE | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-AQOR | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-AQGO | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-AQGR | 20 (40 μL) | 200 μL |
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| MYH14-SIGLEC16-20-AQAQ | 20 (40 μL) | 200 μL |
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MYH14 Gene Summary
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-14 (MYO14). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Myosin Heavy Chain 14
Chromosome: CHR19: 50706884 -50813801
Locus: 19q13.33
SIGLEC16 Gene Summary
The Sialic Acid Binding Ig Like Lectin 16 (gene/pseudogene) (SIGLEC16) gene is located on chr19 :50472911-50479076 at 19q13.33.
Gene Name: Sialic Acid Binding Ig Like Lectin 16 (gene/pseudogene)
Chromosome: CHR19: 50472911 -50479076
Locus: 19q13.33
Gene Diseases
The MYH14 SIGLEC16 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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