NAP1L4-CARS Fusion FISH Probe
The NAP1L4-CARS Fusion FISH Probe is used to confirm a fusion of the NAP1L4 and CARS genes. The fusion of the NAP1L4 and CARS genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NAP1L4-CARS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-RERE | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-REOR | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-REGO | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-REGR | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-REAQ | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-ORRE | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-OROR | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-ORGO | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-ORAQ | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-GORE | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-GOOR | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-GOGO | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-GOGR | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-GOAQ | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-GRRE | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-GROR | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-GRGO | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-GRGR | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-GRAQ | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-AQRE | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-AQOR | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-AQGO | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-AQGR | 20 (40 μL) | 200 μL |
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| NAP1L4-CARS-20-AQAQ | 20 (40 μL) | 200 μL |
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CARS Gene Summary
This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Gene Name: Cysteinyl-tRNA Synthetase
Chromosome: CHR11: 3022151 -3078681
Locus: 11p15.4
NAP1L4 Gene Summary
This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008]
Gene Name: Nucleosome Assembly Protein 1 Like 4
Chromosome: CHR11: 2965659 -3013607
Locus: 11p15.4
Gene Diseases
The NAP1L4 CARS Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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