NCK1-HEBP1 Fusion FISH Probe
The NCK1-HEBP1 Fusion FISH Probe is used to confirm a fusion of the NCK1 and HEBP1 genes. The fusion of the NCK1 and HEBP1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NCK1-HEBP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-RERE | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-REOR | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-REGO | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-REGR | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-REAQ | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-ORRE | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-OROR | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-ORGO | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-GORE | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-GOOR | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-GOGO | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-GOGR | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-GRRE | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-GROR | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-GRGO | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-GRGR | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-AQRE | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-AQOR | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-AQGO | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-AQGR | 20 (40 μL) | 200 μL |
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| NCK1-HEBP1-20-AQAQ | 20 (40 μL) | 200 μL |
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NCK1 Gene Summary
The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Jun 2010]
Gene Name: NCK Adaptor Protein 1
Chromosome: CHR3: 136581049 -136667968
Locus: 3q22.3
HEBP1 Gene Summary
The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells. [provided by RefSeq, Jul 2008]
Gene Name: Heme Binding Protein 1
Chromosome: CHR12: 13127798 -13153243
Locus: 12p13.1
Gene Diseases
The NCK1 HEBP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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