NCKAP5-ERBB4 Fusion FISH Probe
The NCKAP5-ERBB4 Fusion FISH Probe is used to confirm a fusion of the NCKAP5 and ERBB4 genes. The fusion of the NCKAP5 and ERBB4 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NCKAP5-ERBB4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-RERE | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-REOR | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-REGO | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-REGR | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-OROR | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-GORE | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-GROR | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| NCKAP5-ERBB4-20-AQAQ | 20 (40 μL) | 200 μL |
|
ERBB4 Gene Summary
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Gene Name: Erb-b2 Receptor Tyrosine Kinase 4
Chromosome: CHR2: 212240441 -213403352
Locus: 2q34
NCKAP5 Gene Summary
The NCK Associated Protein 5 (NCKAP5) gene is located on chr2 :133429371-134326031 at 2q21.2.
Gene Name: NCK Associated Protein 5
Chromosome: CHR2: 133429371 -134326031
Locus: 2q21.2
Gene Diseases
The NCKAP5 ERBB4 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|