NCKAP5L-BCDIN3D Fusion FISH Probe
The NCKAP5L-BCDIN3D Fusion FISH Probe is used to confirm a fusion of the NCKAP5L and BCDIN3D genes. The fusion of the NCKAP5L and BCDIN3D genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NCKAP5L-BCDIN3D-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-RERE | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-REOR | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-REGO | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-REGR | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-REAQ | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-ORRE | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-OROR | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-ORGO | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-ORAQ | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-GORE | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-GOOR | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-GOGO | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-GOGR | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-GOAQ | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-GRRE | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-GROR | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-GRGO | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-GRGR | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-GRAQ | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-AQRE | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-AQOR | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-AQGO | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-AQGR | 20 (40 μL) | 200 μL |
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| NCKAP5L-BCDIN3D-20-AQAQ | 20 (40 μL) | 200 μL |
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NCKAP5L Gene Summary
The NCK Associated Protein 5 Like (NCKAP5L) gene is located on chr12 :50184928-50222208 at 12q13.12.
Gene Name: NCK Associated Protein 5 Like
Chromosome: CHR12: 50184928 -50222208
Locus: 12q13.12
BCDIN3D Gene Summary
This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs. [provided by RefSeq, Apr 2017]
Gene Name: BCDIN3 Domain Containing RNA Methyltransferase
Chromosome: CHR12: 50229825 -50236912
Locus: 12q13.12
Gene Diseases
The NCKAP5L BCDIN3D Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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