NCKIPSD-IP6K2 Fusion FISH Probe
The NCKIPSD-IP6K2 Fusion FISH Probe is used to confirm a fusion of the NCKIPSD and IP6K2 genes. The fusion of the NCKIPSD and IP6K2 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NCKIPSD-IP6K2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-RERE | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-REOR | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-REGO | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-REGR | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-REAQ | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-ORRE | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-OROR | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-ORGO | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-ORAQ | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-GORE | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-GOOR | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-GOGO | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-GOGR | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-GOAQ | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-GRRE | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-GROR | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-GRGO | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-GRGR | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-GRAQ | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-AQRE | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-AQOR | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-AQGO | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-AQGR | 20 (40 μL) | 200 μL |
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| NCKIPSD-IP6K2-20-AQAQ | 20 (40 μL) | 200 μL |
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IP6K2 Gene Summary
This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Inositol Hexakisphosphate Kinase 2
Chromosome: CHR3: 48725435 -48754711
Locus: 3p21.31
NCKIPSD Gene Summary
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Gene Name: NCK Interacting Protein With SH3 Domain
Chromosome: CHR3: 48711277 -48723334
Locus: 3p21.31
Gene Diseases
The NCKIPSD IP6K2 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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