NCOA6-LSM1 Fusion FISH Probe
The NCOA6-LSM1 Fusion FISH Probe is used to confirm a fusion of the NCOA6 and LSM1 genes. The fusion of the NCOA6 and LSM1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NCOA6-LSM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-RERE | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-REOR | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-REGO | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-REGR | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-REAQ | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-ORRE | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-OROR | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-ORGO | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-GORE | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-GOOR | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-GOGO | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-GOGR | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-GRRE | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-GROR | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-GRGO | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-GRGR | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-AQRE | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-AQOR | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-AQGO | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-AQGR | 20 (40 μL) | 200 μL |
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| NCOA6-LSM1-20-AQAQ | 20 (40 μL) | 200 μL |
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NCOA6 Gene Summary
The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]
Gene Name: Nuclear Receptor Coactivator 6
Chromosome: CHR20: 33302577 -33413433
Locus: 20q11.22
LSM1 Gene Summary
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011]
Gene Name: LSM1 Homolog, MRNA Degradation Associated
Chromosome: CHR8: 38020858 -38034026
Locus: 8p11.23
Gene Diseases
The NCOA6 LSM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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