NCOA6-SLC10A1 Fusion FISH Probe
The NCOA6-SLC10A1 Fusion FISH Probe is used to confirm a fusion of the NCOA6 and SLC10A1 genes. The fusion of the NCOA6 and SLC10A1 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NCOA6-SLC10A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-RERE | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-REOR | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-REGO | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-REGR | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-REAQ | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-ORRE | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-OROR | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-ORGO | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-GORE | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-GOOR | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-GOGO | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-GOGR | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-GRRE | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-GROR | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-GRGO | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-GRGR | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-AQRE | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-AQOR | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-AQGO | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-AQGR | 20 (40 μL) | 200 μL |
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| NCOA6-SLC10A1-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC10A1 Gene Summary
The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis. [provided by RefSeq, Oct 2011]
Gene Name: Solute Carrier Family 10 Member 1
Chromosome: CHR14: 70242551 -70264006
Locus: 14q24.1
NCOA6 Gene Summary
The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]
Gene Name: Nuclear Receptor Coactivator 6
Chromosome: CHR20: 33302577 -33413433
Locus: 20q11.22
Gene Diseases
The NCOA6 SLC10A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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