NCOR1-RHOU Fusion FISH Probe
The NCOR1-RHOU Fusion FISH Probe is used to confirm a fusion of the NCOR1 and RHOU genes. The fusion of the NCOR1 and RHOU genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NCOR1-RHOU-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-RERE | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-REOR | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-REGO | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-REGR | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-REAQ | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-ORRE | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-OROR | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-ORGO | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-ORAQ | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-GORE | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-GOOR | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-GOGO | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-GOGR | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-GOAQ | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-GRRE | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-GROR | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-GRGO | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-GRGR | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-GRAQ | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-AQRE | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-AQOR | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-AQGO | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-AQGR | 20 (40 μL) | 200 μL |
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| NCOR1-RHOU-20-AQAQ | 20 (40 μL) | 200 μL |
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NCOR1 Gene Summary
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]
Gene Name: Nuclear Receptor Corepressor 1
Chromosome: CHR17: 15933407 -16118874
Locus: 17p12-p11.2
RHOU Gene Summary
This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.[provided by RefSeq, Mar 2011]
Gene Name: Ras Homolog Family Member U
Chromosome: CHR1: 228780393 -228882416
Locus: 1q42.13
Gene Diseases
The NCOR1 RHOU Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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